Archive for the ‘dose’ Category

High Dose Lipitor Reduces Artery Inflammation

Tuesday, May 13th, 2008

High doses of Pfizer Inc’s Lipitor was more effective than low doses of the cholesterol fighter in reducing arterial inflammation in patients with carotid artery disease, according to a small, 12-week study.

Inflammation in arteries has been associated with an increased risk of stroke.

Inflammation and emboli, or small blood clots, were significantly reduced in patients treated with 80 milligrams of Lipitor compared with those who received 10 mg of the drug each day for 12 weeks, said researchers, who presented the data at the American College of Cardiology scientific meeting on Monday.

The study divided 40 patients with diseased carotid arteries into the two groups. The artery was examined for changes in inflammation at six weeks and 12 weeks using a unique contrast agent with high-resolution magnetic resonance imaging (MRI).

While the 80 mg Lipitor, known generically as atorvastatin, reduced inflammation, researchers appeared even more enthusiastic about the technique used to measure the results.

The arteries were viewed using Ultra Small Particles of Iron Oxide, or USPIO-enhanced, high-resolution MRI.

“The real star of this study is this new way of imaging, which allows you to zero in on what is actually going on in these arteries,” said Dr Jonathan Gillard, one of the study’s lead researchers.

The study demonstrates that if you treat patients who have inflammation of the carotid artery with “a high dose of atorvastatin, you substantially reduce the amount of inflammation and risk of stroke, whereas low dose atorvastatin does not reduce risk,” Gillard said.

“Thanks to this imaging technique, we can now figure out which patients need the aggressive treatment before we begin our therapy,” he added.

Lipitor, which lowers levels of LDL, or bad, cholesterol in the blood, is the world’s top-selling prescription medicine with some $12 billion in annual sales.

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How Should I Take Lipitor?

Sunday, May 4th, 2008

Take this medication on the dot as it was positive for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor of the Church. Follow the directions on your prescription label.

Take Lipitor with a full glass of water supply.

Lipitor (Atorvastatin) can be taken with or without food.

Lipitor is normally taken erstwhile a day. Try to take your dose at the same time each day. Follow your doctor’s instructions.

To be indisputable this medication is serving your status, your blood will motivation to be tested on a regular basis. Your liver function may besides need to be tested. Do non miss whatever scheduled appointments.

In rare cases, Lipitor can causal agency a condition that results in the breakdown of skeletal musculus tissue. This condition can lead to kidney failure. Call your doctor at once if you possess unexplained muscle pain or tenderness, muscle weakness, pyrexia or influenza symptoms, and dark dyed urine.

Lipitor is only part of a complete program of treatment that also includes diet, example, and weight control. Follow your diet, medication, and exercise routines very closely.

You whitethorn need to take Lipitor on a long-term cornerstone for the treatment of high cholesterin.

Shop Lipitor at room temperature, protected from moisture, heat, and light.What happens if I miss a venereal infection?

Take the missed dosage as shortly as you remember. If it is almost time for the next dot, skip the missed dose and take only the next on a regular basis scheduled dose. Do not take duplicate medicine to make up the lost dose.

What happens if I overdose?

Seek emergency aesculapian attention if you cerebrate you ingest used likewise much of this music.

An overdose of Lipitor is not expected to produce life-threatening symptoms.

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