Archive for December, 2008

Low Carb Cholesterol Diet Will Produce Results

Sunday, December 28th, 2008

Although necessary for our bodies to function properly, many people worry about high cholesterol levels and the effect it may have their health. Our bodies produce both “good” (HDL) and “bad”(LDL) cholesterol. For proper health, the goal is to increase levels of “good” cholesterol and reduce our levels of “bad” cholesterol. Both of these goals can be accomplished by utilizing a low carb cholesterol diet.

The mechanics of the low carb cholesterol diet are simple. This type of diet works by reducing or completely cutting out fat- and sugar-laden foods. When sugar and insulin levels rise, body fat also rises. The triggering factor behind this rise is excess carbohydrates, found in sugars and starches. Too much sugar and body fat can lead to other health problems such as heart disease and diabetes.

Cholesterol is present in a number of foods, especially those containing saturated or trans-fats. A low carb cholesterol diet that reduces sweets and saturated and trans-fats will result in a lowering of both body fat and bad cholesterol levels. Most overweight patients have elevated cholesterol levels and would benefit from implementing a low carb low cholesterol diet.

By considerably decreasing the body’s insulin level, low carb cholesterol diet foods trigger the use of excess fat and sugars already available in your body. This will consequently cause you to lose weight at a much faster rate than possible with ordinary diets.

If you decide to try a low carb cholesterol diet, you should know that you can eat almost anything, provided you stick with foods that are low in carbohydrates and sugars. You should do a little research into finding out what foods contain high levels of carbs and cholesterol and you’ll be better prepared to avoid them or replace them with healthier options.

Thanks to increased awareness regarding cholesterol and heart health, there are a lot of foods readily available that can be used in a low carb cholesterol diet. Foods that are usually high in starch like pasta are now available with reduced carbohydrates. This allows people who care about their health and weight to take pleasure in eating these products and decrease their cholesterol at the same time.

If you want to lose weight, feel healthier, have more energy and get faster results on your cholesterol levels, exercise is an important key factor. Double check with your doctor before you begin any new eating plan, including a low carb cholesterol diet, to be absolutely certain this is the right choice for you. If you are pregnant or nursing, or if you already have a medical condition that might limit you, it is extremely important for you to get the go-ahead from your doctor.

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Got Low Cholesterol?

Friday, December 26th, 2008

Statins still might help

Heart attacks and strokes are cut in half of people who took the drug but didn’t need it

A study out this month raises questions about who might benefit from taking cholesterol-lowering drugs called statins. Between 16 million and 20 million Americans already take such drugs.

The study, reported online in the New England Journal of Medicine, suggests that older adults may reduce their risk of heart attacks and strokes by taking a statin even if their cholesterol level is normal.

Half the patients in the study took the statin rosuvastatin (brand name: Crestor), and half took an identical-looking but inactive drug.

Those in the statin group were about half as likely as the others to have a heart attack or stroke during the study. After two years, the results were dramatic enough for researchers to halt the study three years early.

We asked Dr. Jody Welborn, a cardiologist with the Providence Heart and Vascular Institute and The Oregon Clinic, to help put the new findings into perspective. Her answers were edited for clarity and brevity.

What’s the news here?

This is an important study. It gives us more information about statins and their role in treating and preventing heart disease. And it does expand our target group of patients for statins.

More knowledge is important because about half of heart attacks occur in patients with low cholesterol, or cases where we plain don’t know why it happened.

What caveats go with the findings?

The study was large — nearly 18,000 participants — but not a cross section of adults. It included men 50 or older and women 60 or older. They had normal cholesterol but high levels of C-reactive protein, or CRP, a sign of inflammation.

The study doesn’t address the value of statins in younger people. Researchers found benefits over the short-term, but we don’t know whether the benefit will be prolonged or whether the risks will become more apparent after more time.

If I’m a healthy adult with normal cholesterol, should I consider taking a statin?

Not necessarily. Unfortunately, the study doesn’t directly answer that question.

For most doctors, this won’t dramatically alter their prescribing pattern. But even if the new findings serve as a starting point for the conversation about how to prevent heart disease, that’s a good thing. We need to do more to prevent heart disease, as opposed to treating it later.

How will this study change the way you treat heart patients? Do they bring it up?

You take a deep breath and brace for a flurry of phone calls and questions. Primary care doctors probably hear this more than cardiologists.

What most patients want to know is: How will this benefit me?

OK, how will this benefit me?

It’s a hard question. Measurement of cardiac risk is not an exact science. It involves many factors: age, gender, diet, family history, smoking, blood pressure, cholesterol, diabetes, sedentary lifestyle, etc.

Considering all these factors, I try to estimate the patient’s heart risk as low, moderate or high.

We talk about lifestyle changes first: quitting smoking, exercise, diet, things like monitoring weight, girth and blood pressure. Then I introduce statins, their pros and cons. And we come to a decision based on back-and-forth discussion.

What’s the downside of taking statins?

The most common side effect — in 1 percent to 5 percent of patients — is muscle aches. By itself, that is tolerable to most patients. But in rare cases, the patient develops severe muscle breakdown, or rhabdomyolysis.

Then there’s cost. Statins are a drug you take for the rest of your life. Crestor costs about $3 a pill. Some statins are less expensive and available in generic form. But if we put a gazillion people on statins, we’re going to be spending a lot. By the study’s estimate, we’d be spending an estimated $500,000 a year to prevent one cardiac death.

The study also detected a slight trend toward developing diabetes in the group taking statins. It was a tiny difference, but that needs to be watched over time.

Part of the confusion comes from a blurring of relative and absolute risk. Help sort that out.

It is confusing. This study found nearly a 50 percent reduction in the relative risk of a heart attack or stroke in the group taking a statin, compared with the group that didn’t. But the absolute risk of having a heart attack or stroke was low in both groups.

So you can look at the result in two ways. Taking a statin lowered the absolute risk of a heart attack from 1.8 percent to 0.9 percent. That may not sound like much of a change. But if you say that taking a statin cut the relative risk in half, it sounds pretty significant.

Are all statins the same?

They’re not identical. This study looked only at Crestor. But in my opinion, what the study found is a statin effect, not just a Crestor effect.

The clinical trial was sponsored by AstraZeneca, the pharmaceutical company that makes Crestor.

Does that make you question the findings?

A qualified no. Anytime a study is sponsored by a drug maker, you look carefully at the data because you’re concerned about a possible bias. In this instance, I believe the data.

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HIV Tests Not Yet As Routine As Cholesterol Checks

Wednesday, December 24th, 2008

Two years after the government urged that HIV tests become as common as cholesterol checks, there are small gains but still one in five people infected with the AIDS virus does not know it, scientists said Nov. 20.

Eleven states that once required special consent for HIV testing have changed their laws, a key step to making an HIV test part of the standard battery that patients expect.

But HIV specialists meeting Nov. 20 said other barriers include physician confusion about the ease of today’s rapid tests, which can cost as little as $15, even though many patients seem to accept them.

No more than 100 of the nation’s 5,000 emergency rooms routinely test for HIV in patients who are not critically ill, said Dr. John Bartlett of Johns Hopkins University, who co-chaired the Forum for Collaborative HIV Research meeting. Yet because so many HIV patients are poor or uninsured, ERs are the health care setting most likely to find them.

And while every pregnant woman is supposed to be tested so her fetus can be protected if the mother is found to have AIDS, about 40 percent are not tested, he said.

“Those are what we call missed opportunities,” Bartlett said. Today, the test is “much better, it’s much easier, it’s much cheaper. The treatment is really great now.”

Just over 1.1 million Americans are estimated to have HIV and 232,000 do not know it, according to the Centers for Disease Control and Prevention.

The CDC for years recommended routine testing mainly for people at high-risk, such as injecting drug users. Then, finally, came drugs potent enough to keep HIV patients healthy for years, postponing the slide into full-blown AIDS. Yet nearly half of new infections still were being discovered too late for patients to benefit. Not to mention that people who don’t know they’re infected unwittingly spread the virus.

So in September 2006, the CDC recommended routine testing for everyone ages 13 to 64, whether they think they’re at risk for HIV or not.

There is no nationwide data yet on the new guidelines’ impact, CDC’s Dr. Bernard Branson told The Associated Press.

But Branson listed encouraging signs:

– New York City’s Health and Hospitals Corp., the nation’s largest municipal health system, has nearly tripled HIV testing, and late diagnoses have dropped by about a third.
– New York’s state Medicaid program has increased testing by 30 percent.
– Early results from a federal survey suggest 2.4 million more people in 2007 said they had ever been tested for HIV than said so in 2006.
– President George W. Bush in October signed a law allowing Veterans Administration clinics to ease testing requirements.
“I don’t think anyone at CDC anticipated that we would test the whole country in a single year,” Branson said.

But in pilot projects around the country, “people are taking the recommendations to heart and implementing them as much as was feasible for them,” he added. Moreover, “we find people are very receptive to being tested, and there was concern about that before.”

Indeed, studies presented suggest more than 80 percent of emergency-room patients were amenable to HIV tests, while most ER workers opposed testing them. Why? Presumably because ERs are so busy, and there is confusion about how much HIV counseling is needed.

Bartlett demonstrated how to quickly give people a chance to either opt out or request counseling: “Mr. Jones, you’re going to have a cholesterol test, a blood count, and an HIV test – and by the way we do the HIV test on everybody because that’s what the CDC has recommended. Is there any part of this that you want more information about or you don’t want to have?”

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Side Effects From Lipitor

Monday, December 22nd, 2008

Statins may be effective in lowering cholesterol – but at what cost?  With the high price of statin drugs and potentially undesirable side effects, many people have begun looking into supplements as an alternative to lowering cholesterol.

Omega-3s are essential fatty acids, meaning they can’t be manufactured by the human body yet they are essential for good health.  Omega-3s lower triglycerides, increase HDL “good” cholesterol, and lower high blood pressure.  The American Heart Association recommends eating fish twice a week to get your omega-3s, or you can take it as a supplement.  One new study by Professor Luigi Tavazzi and Professor Gianni Tognoni, GISSI-HF Coordinating Centre, ANMCO Research Centre, Florence, Italy compared the effectiveness of taking a one-a-day capsule of omega-3 polyunsaturated fatty acids to taking statins.  The results concluded that taking omega-3 can effectively reduce hospital admission and mortality rate for cardiovascular issues in heart failure patients.  Statins, on the other hand, proved to not have any affect in the mortality outcome of patients.

An herbal supplement called red yeast rice has been used in traditional Chinese medicine for centuries.  Red yeast rice contains lovastatin, the same active ingredient as the prescription statin drugs.  Made from a rice extract fermented with red yeast, it is shown to significantly lower LDL levels.  In a study from the July Mayo Clinic Proceedings, one test group was given prescription statin drugs with written diet and exercise guidelines.  A second group was given red yeast rice, omega-3 supplements and in-depth diet, exercise and relaxation counseling.  The findings were almost exactly the same, with a drop in LDL levels of 40 percent for each group.  Despite these results, red yeast rice may also cause similar side effects as statins due to the same active ingredient lovastatin.  Additionally, it is difficult to know the exact quality of red yeast rice because it is not closely regulated by the FDA.

While a lot of attention has been put on lowering LDL levels, research is showing that raising HDL cholesterol is just as important.  It is thought that HDL cholesterol picks up excess bad cholesterol in your blood and takes it back to your liver for disposal.  Niacin, or vitamin B-3, has long been used to increase HDL levels.  Studies show that niacin reduces LDL levels up to 20% and boosts HDL cholesterol by about 35%.  Niacin also seems to lower lipoprotein A, which is another risk factor for atherosclerosis.  Despite these benefits, niacin may cause flushing and raised blood sugar.  It should be taken under the supervision of a health care professional.

Additional supplements that may have cholesterol lowering effects include blond psyllium seed husks, artichoke leaf, soluble fiber, plant sterols, garlic, flaxseed, Metamucil and policosanol to name a few.

Have you been diagnosed with high cholesterol?  Have you decreased your cholesterol levels?  If so, by what means?  Have you found that “natural” supplements have helped you establish lower cholesterol levels without side effects?  Share your experiences.

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What Do Your Cholesterol Numbers Mean?

Sunday, December 21st, 2008

Everyone age 20 and older should have their cholesterol measured at least once every 5 years. It is best to have a blood test called a “lipoprotein profile” to find out your cholesterol numbers. This blood test is done after a 9- to 12-hour fast and gives information about your:

* Total cholesterol
* LDL (bad) cholesterol – the main source of cholesterol buildup and blockage in the arteries
* HDL (good) cholesterol – helps keep cholesterol from building up in the arteries
* Triglycerides – another form of fat in your blood

If it is not possible to get a lipoprotein profile done, knowing your total cholesterol and HDL cholesterol can give you a general idea about your cholesterol levels. If your total cholesterol is 200 mg/dL*

Or more or if your HDL is less than 40 mg/dL, you will need to have a lipoprotein profile done. See how your cholesterol numbers compare to the tables below.

Total Cholesterol……… Level Category
Less than 200 mg/dL….. Desirable
200-239 mg/dL…………….. Borderline high
240 mg/dL and above….. High

LDL Cholesterol Level….. LDL Cholesterol Category
Less than 100 mg/dL………… Optimal
100-129 mg/dL……………….. Near optimal/above Optimal
130-159 mg/dL……………….. Borderline high
160-189 mg/dL……………….. High
190 mg/dL and above Very high

HDL (good) cholesterol protects against heart disease, so for HDL, higher numbers are better.A level less than 40 mg/dL is low and is considered a major risk factor because it increases your risk for developing heart disease. HDL levels of 60 mg/dL or more help to lower your risk for heart disease. Triglycerides can also raise heart disease risk.

Levels that are borderline high (150-199 mg/dL) or high (200 mg/dL or more) may need treatment in some people.

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What Is Your Risk of Developing Heart Disease or Having a Heart Attack?

Saturday, December 20th, 2008

In general, the higher your LDL level and the more risk factors you have (other than LDL), the greater your chances of developing heart disease or having a heart attack. Some people are at high risk for a heart attack because they already have heart disease. Other people are at high risk for developing heart disease because they have diabetes (which is a strong risk factor) or a combination of risk factors for heart disease. Follow these steps to find out your risk for developing heart disease.

Step 1 :

Check the table below to see how many of the listed risk factors you have; these are the risk factors that affect your LDL goal.

Major Risk Factors That Affect Your LDL Goal

* Cigarette smoking
* High blood pressure (140/90 mmHg or higher or on blood pressure medication)
* Low HDL cholesterol (less than 40 mg/dL)*
* Family history of early heart disease (heart disease in father or brother before age 55; heart disease in mother or sister before age 65)
* Age (men 45 years or older; women 55 years or older)

Even though obesity and physical inactivity are not counted in this list, they are conditions that need to be corrected.

Step 2 :

How many major risk factors do you have? If you have 2 or more risk factors in the table above, use the risk scoring tables on the back page (which include your cholesterol levels) to find your risk score. Risk score refers to the chance of having a heart attack in the next 10 years, given as a percentage.

Step 3 :

Use your medical history, number of risk factors, and risk score to find your risk of developing heart disease or having a heart attack in the table below.

If You Have………………………………………………..You Are in Category

Heart disease, diabetes, or risk score more than 20%*……..I. High Risk
2 or more risk factors and risk score 10-20%…………II. Next Highest Risk
2 or more risk factors and risk score less than 10% …III. Moderate Risk
0 or 1 risk factor………………………………………………IV. Low-to-Moderate Risk

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Treating High Cholesterol

Friday, December 19th, 2008

The main goal of cholesterol-lowering treatment is to lower your LDL level enough to reduce your risk of developing heart disease or having a heart attack. The higher your risk, the lower your LDL goal will be. To find your LDL goal, see the box for your risk category below. There are two main ways to lower your cholesterol:

* Therapeutic Lifestyle Changes (TLC)-includes a cholesterol-lowering diet (called the TLC diet), physical activity, and weight management. TLC is for anyone whose LDL is above goal.
* Drug Treatment-if cholesterol-lowering drugs are needed, they are used together with TLC treatment to help lower your LDL.

If you are in…

Category I, High Risk, your LDL goal is less than 100 mg/dL. You will need to begin the TLC diet to reduce your high risk even if your LDL is below 100 mg/dL. If your LDL is 100 mg/dL or above, you will need to start drug treatment at the same time as the TLC diet. If your LDL is below 100 mg/dL, you may also need to start drug treatment together with the TLC diet if your doctor finds your risk is very high, for example if you have had a recent heart attack or have both heart disease and diabetes.

Category II, Next Highest Risk, your LDL goal is less than 130 mg/dL. If your LDL is 130 mg/dL or above, you will need to begin treatment with the TLC diet. If your LDL is 130 mg/dL or more after 3 months on the TLC diet, you may need drug treatment along with the TLC diet. If your LDL is less than 130 mg/dL, you will need to follow the heart-healthy diet for all Americans, which allows a little more saturated fat and cholesterol than the TLC diet.

Category III, Moderate Risk, your LDL goal is less than 130 mg/dL. If your LDL is 130 mg/dL or above, you will need to begin the TLC diet. If your LDL is 160 mg/dL or more after you have tried the TLC diet for 3 months, you may need drug treatment along with the TLC diet. If your LDL is less than 130 mg/dL, you will need to follow the heart-healthy diet for all Americans.

Category IV, Low-to-Moderate Risk, your LDL goal is less than 160 mg/dL. If your LDL is 160 mg/dL or above, you will need to begin the TLC diet. If your LDL is still 160 mg/dL or more after 3 months on the TLC diet, you may need drug treatment along with the TLC diet to lower your LDL, especially if your LDL is 190 mg/dL or more. If your LDL is less than 160 mg/dL, you will need to follow the heart-healthy diet for all Americans.

To reduce your risk for heart disease or keep it low, it is very important to control any other risk factors you may have such as high blood pressure and smoking.

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Lowering Cholesterol With Therapeutic Lifestyle Changes (TLC)

Thursday, December 18th, 2008

TLC is a set of things you can do to help lower your LDL cholesterol. The main parts of TLC are:

The TLC Diet. This is a lowsaturated- fat, low-cholesterol eating plan that calls for less than 7 percent of calories from satrated fat and less than 200 mg of dietary cholesterol per day. The TLC diet recommends only enough calories to maintain a desirable weight and avoid weight gain. If your LDL is not lowered enough by reducing saturated fat and cholesterol intakes, the amount of soluble fiber in your diet can be increased. Certain food products that contain plant stanols or plant sterols (for example, cholesterol lowering margarines) can also be added to the TLC diet to boost its LDL-lowering power.

Weight Management. Losing weight if you are overweight can help lower LDL and is especially important for those with a cluster of risk factors that includes high triglyceride and/or low HDL levels and being overweight with a large waist measurement (more than 40 inches for men and more than 35 inches for women).

Physical Activity. Regular physical activity (30 minutes on most, if not all, days) is recommended for everyone. It can help raise HDL and lower LDL and is especially important for those with high triglyceride and/or low HDL levels who are overweight with a large waist measurement.

Drug Treatment

Even if you begin drug treatment to lower your cholesterol, you will need to continue your treatment with lifestyle changes. This will keep the dose of medicine as low as possible, and lower your risk in other ways as well. There are several types of drugs available for cholesterol lowering including statins, bile acid sequestrants, nicotinic acid, fibric acids, and cholesterol absorption inhibitors. Your doctor can help decide which type of drug is best for you. The statin drugs are very effective in lowering LDL levels and are safe for most people. Bile acid sequestrants also lower LDL and can be used alone or in combination with statin drugs. Nicotinic acid lowers LDL and triglycerides and raises HDL. Fibric acids lower LDL somewhat but are used mainly to treat high triglyceride and low HDL levels. Cholesterol absorption inhibitors lower LDL and can be used alone or in combination with statin drugs.

Once your LDL goal has been reached, your doctor may prescribe treatment for high triglycerides and/or a low HDL level, if present. The treatment includes losing weight if needed, increasing physical activity, quitting smoking, and possibly taking a drug.

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Cut Out or Lower Your Cholesterol Medication Doses

Wednesday, December 17th, 2008

I have high blood pressure and my LDL cholesterol level was very high. My doctor is pleased with my most recent numbers; but I take so many pills. What can I do to cut out or lower the dose of some of these medications?

We’ve gotten used to taking pills for much that ails us, but these days, the medicine cabinet is looking like a rogues’ gallery. We don’t lack for alternatives. Plenty of research shows that exercise, diet and other lifestyle changes are effective weapons against many chronic conditions. Here are ways to help you reduce your pill count and get the results you and your doctor are looking for:

To help lower your blood pressure, take your pick: lose some weight, get more exercise, eat less sodium, change your diet. They all work.

If you’re heavy, each two pounds of weight loss translates to a 1 mm Hg drop in systolic (the top number) and diastolic (the bottom number) blood pressure. Regular exercise can even lower your blood pressure if you don’t lose weight.

Eliminating about three-quarters of a teaspoon of salt (1.8 grams of sodium) from your diet each day may drop your systolic reading by 5 points and the diastolic by 3. Trials of vegetarian diets have shown they can reduce systolic blood pressure by 5 mm Hg.

The Dietary Approaches to Stop Hypertension (DASH) diet can lower systolic blood pressure by 12 points and diastolic pressure by 5. DASH dieting involves eating fruits and vegetables (seven to nine servings a day) and low-fat dairy products (two to three servings a day), plus whole grains, nuts, poultry and fish, all while keeping saturated fat, red meat and sweets to a minimum.

Any of these strategies will also make blood-pressure-lowering medication more effective. Whether they can replace the pills depends on how high your blood pressure is. But weight loss, exercise and diet can make lower dosages possible and perhaps eliminate the need for medication altogether.

You can adjust your diet in several ways to lower levels of “bad” LDL cholesterol. Your LDL level may drop by 5 percent if you keep foods high in saturated fat (meat and full-fat dairy products) off the menu. Every additional gram of soluble fiber per day may reduce LDL levels by about 2 mg/dL. Diets that have included margarines fortified with sterols – compounds that block cholesterol absorption – have brought about LDL drops of 10 to 20 percent in some studies. Low-fat diets heavy on the vegetables (10 servings a day) and legumes and nuts (4 servings a day) have dialed down LDL levels by almost 10 percent.

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What Affects Cholesterol Levels?

Monday, December 15th, 2008

A variety of things can affect cholesterol levels. These are things you can do something about:

* Diet. Saturated fat and cholesterol in the food you eat make your blood cholesterol level go up. Saturated fat is the main culprit, but cholesterol in foods also matters. Reducing the amount of saturated fat and cholesterol in your diet helps lower your blood cholesterol level.
* Weight. Being overweight is a risk factor for heart disease. It also tends to increase your cholesterol. Losing weight can help lower your LDL and total cholesterol levels, as well as raise your HDL and lower your triglyceride levels.
* Physical Activity. Not being physically active is a risk factor for heart disease. Regular physical activity can help lower LDL (bad) cholesterol and raise HDL (good) cholesterol levels. It also helps you lose weight. You should try to be physically active for 30 minutes on most, if not all, days.

Things you cannot do anything about also can affect cholesterol levels. These include:

* Age and Gender. As women and men get older, their cholesterol levels rise. Before the age of menopause, women have lower total cholesterol levels than men of the same age. After the age of menopause, women’s LDL levels tend to rise.
* Heredity. Your genes partly determine how much cholesterol your body makes. High blood cholesterol can run in families.

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